Young adults who received a Pfizer COVID-19 vaccine showed elevated spike protein production a year or more after vaccination — that’s significantly longer than the spike protein was expected to remain in the body — a peer-reviewed study showed.
The study, published last week in Immunity, Inflammation and Disease, found that participants exhibited elevated levels of multiple proinflammatory cytokines — proteins that help regulate the immune system — signifying “the persistence of the humoral immune response to messenger RNA (mRNA) vaccines.”
According to the study, “the persistent production of spike protein and highly inflammatory nature of mRNA-lipid nanoparticle” may account for the elevated cytokine levels.
Lipid nanoparticles are intended to deliver mRNA to human cells. But they’ve also been found to deliver DNA contaminants, contained within mRNA COVID-19 vaccines, throughout the body.
Study ‘raises important questions’ about long-term impact of COVID shots
“This study raises important questions about the long-term immunological imprinting of mRNA COVID-19 vaccines in healthy young adults,” TrialSite News reported.
TrialSite News founder and CEO Daniel O’Connor said the study’s findings “highlight the urgent need for spike protein clearance and biodistribution studies — especially in young males and older adults — whose immune responses appear disproportionately affected.”
Karl Jablonowski, Ph.D., senior research scientist for Children’s Health Defense (CHD), said that while the study design — a longitudinal study of 84 people without a control group — “is not the strongest of designs,” he said the study nevertheless presents “evidence with strong implications.”
“Months- or even years-long production of spike protein has some really scary prospects, one of which is T-cell exhaustion,” Jablonowski said. This can result in a situation where the body cannot effectively fight viruses or cancer. “Persistent exposure to antigens will exhaust the T-cells and inhibit their natural function.”
Epidemiologist Nicolas Hulscher said the study’s findings “are not unexpected,” citing 130 peer-reviewed studies that have identified the persistent presence of spike protein in the human body.
Hulscher said long-term exposure to spike proteins may result in symptoms similar to those experienced by people diagnosed with long COVID.
A preprint by Yale University researchers published in February found that people thought to be experiencing long COVID may be suffering from post-vaccination syndrome. The study also showed that the spike protein from the COVID-19 vaccine persisted in the blood of at least one person 709 days after vaccination — a significantly longer time than previously measured.
Jablonowski noted that the study’s findings may also point to a broader safety signal that may be evident in COVID-19 vaccine injury data currently maintained in U.S. government databases.
“It warrants a larger retrospective controlled study, the data for which is mothballed by government or healthcare institutions,” Jablonowski said. “This kind of data is not kept forever. The window to preserve information on the harms of the COVID-19 injections is quickly closing.”
In an interview last month, U.S. Secretary of Health and Human Services (HHS) Robert F. Kennedy Jr. said that HHS sub-agencies were selling patient information — presumably including vaccine injury information — to each other instead of making the information freely accessible.
During the same interview, Kennedy announced the launch of a new agency within the Centers for Disease Control and Prevention (CDC) that will specialize in vaccine injuries.
‘Significant increase’ in cytokines linked to autoimmune disorders
According to the new study, a “significant increase in weight and body mass index was observed overall” among study participants, as were “significant increases” in “several cytokines.”
In an analysis published on Substack, Hulscher noted that the presence of the TNF-α, IL-1β, IL-6, IL-4, IL-7 and IL-17E cytokines increased in study participants. These cytokines “are associated with chronic inflammation, immune dysregulation, and autoimmune activation.” These increases were “significantly greater” in males, the study authors said.
Increases were also observed in the VEGFA (angiogenesis), FGF2 and IFN-γ cytokines, linked to “vascular remodeling, tissue repair, and persistent immune activation,” and the MCP-1 and MCP-3 cytokines, “associated with chronic inflammation, vascular remodeling, and autoimmunity.”
The study showed that the presence of the macrophage colony-stimulating factor cytokine decreased. This could be a sign of immune system dysregulation, Hulscher wrote.
Brian Hooker, Ph.D., chief scientific officer for CHD, said, “It is a little difficult to tell regarding the increase in cytokines in young adults because they also experienced the greatest increase in overall weight and BMI within the study. Obesity goes hand-in-hand with inflammation.”
“However, even the increases in the cohort of older adults considered alone is concerning and this needs a larger, more comprehensive study using retrospective data from the pandemic,” Hooker said. That data “should be made publicly available as soon as possible for independent analysis.”
According to the study, the persistence of spike protein in the body is fueled by the presence of mRNA and pro-inflammatory lipid nanoparticles. Jablonowski compared this to the impact of medical treatments such as chemotherapy on the human body.
“There are few medical treatments that increase cytokine proinflammatory markers months after administration. Adjuvant chemotherapy is one of them, a therapy specifically designed to kill tissue,” Jablonowski said.
Jablonowski also suggested that self-amplifying mRNA COVID-19 vaccines — recently approved in Japan and the European Union — could exacerbate the presence of spike proteins in the body.
“The cytokine markers described in the paper are a clear sign the immune system is in duress. If persistent production of spike protein is the, or a contributory, cause of this duress, the self-amplifying COVID-19 mRNA vaccines, just approved in Japan and Europe, will amplify that duress.”
Hooker said that the presence of spike protein can also lead to a range of other health risks.
“Increased inflammation leads to so many different conditions associated with the COVID-19 vaccine, including cardiac sequelae and turbo cancers. This definitely contributes to the body of literature supporting a complete withdrawal of all COVID-19 vaccines on the market,” Hooker said.
“As yet another study reveals grave harms linked to the COVID-19 mRNA injections, the case for their immediate removal from the market grows stronger and more urgent,” Hulscher wrote.
A growing number of scientific papers — and scientists — have called for mRNA products to be pulled from the market. A petition by several scientists, still pending before the FDA, calls for the suspension or withdrawal of the mRNA COVID-19 vaccines. Some U.S. states and communities are also considering a ban.
Bypass Big Tech Censors
Two Storms, One Harvest
Every food crisis in living memory has been a one-shock event. The 2008 price spike was a commodity bubble. The 2020 shortages were a logistics failure. The 2022 grain scare was a war on one exporter’s ports. Each time, the system bent, adjusted, and recovered, and each time the experts assured us afterward that global markets are simply too big and too diversified to fail.
What nobody in Washington seems eager to discuss is that 2026 is shaping up to be something the modern food system has never actually faced. Two independent shocks, one climatic and one geopolitical, are converging on the same harvest cycle at the same time. Not sequentially. Simultaneously.
Start with the weather. The Pacific Ocean is currently building toward what forecasters now openly call a record event. NOAA’s Climate Prediction Center puts the odds of at least a strong El Niño near 88 percent, with roughly two in three odds it reaches “very strong” status, the tier reserved for perhaps three or four events in the entire satellite era. Every major global model now projects a median peak in Super El Niño territory, and most of them project it exceeding the 2015-16 event, which until now held the modern record. Sea surface anomalies were already brushing the super threshold in mid-July, months before these events normally peak. The atmosphere has already shifted into El Niño mode, and the event is forecast to crest in late fall and early winter.
This is not about “climate change.” It’s about the standard cycles of weather, and the cycle we’re currently in is one that has likely devastated societies in the past. We’re better prepared as a society today, but not all Americans are equally prepared.
Serious households have started doing the quiet math on their own. Grocery bills tell part of the story, and the forecast maps tell the rest, which is why long-term food storage has moved from fringe hobby to mainstream line item in the family budget, with established suppliers like Heaven’s Harvest seeing demand from people who five years ago would have rolled their eyes at the idea. That instinct is not paranoia. It is pattern recognition, and the pattern is worth walking through carefully.
Editor’s Note: Heaven’s Harvest IS a sponsor, but the warnings of this article are real and would be written even if we didn’t have a survival food sponsor. With that said, those who take advantage of what they offer can use promo code “Patriot” for 15% off.
The Fertilizer Clock Is Already Running
While the Pacific warms, the second shock has been unfolding in the Strait of Hormuz. The conflict with Iran turned the world’s most important energy chokepoint into a contested waterway, and the consequences reach far beyond the gas pump. Roughly a third of global fertilizer trade moves through Hormuz, and the disruption sent urea prices up 86 percent year over year by March, with a 53 percent jump in a single month.
The World Bank projects energy prices rising about 24 percent in 2026 and fertilizer about 31 percent. By its own accounting, fertilizer prices ran 35 percent higher in the first five months of this year than the same period last year.
Here is the mechanism the nightly news will not explain. Fertilizer is not a grocery item. It is a time-delayed input. The nitrogen a farmer in Iowa or Punjab could not afford to apply this spring does not show up as a problem this spring. It shows up as a thinner harvest six to twelve months later.
The World Bank’s own food security brief concedes that the effects of reduced applications earlier this season “are likely to become visible only later in harvest outcomes.” Translate that from institutional language into plain English and it means this. The damage is already done, it is already in the ground, and we are simply waiting for it to arrive on the shelf.
Now check the calendar. Six to twelve months from the spring planting season lands us squarely in late 2026 and early 2027. Which is precisely when the strongest El Niño in the instrumental record is forecast to peak, bringing its signature droughts to Southeast Asia, Australia, southern Africa, northern Brazil, and South Asia, the very regions that grow the world’s rice, sugar, and oilseeds.
The World Bank warns openly that a strong El Niño “could disrupt multiple crop belts simultaneously” on top of the conflict-driven input costs. Their baseline projection assumes the Middle East disruptions ease by autumn. What in the last two years of Middle East history suggests that assumption is safe?
The System Has No Slack Left
The comfortable answer is that global markets always adjust. But adjustment requires slack, and the slack is gone. Global cereal production is expected to decline from last year’s records even before El Niño does its work. The UN World Food Programme, hardly a den of right-wing preppers, is calling this the most significant disruption to its supply chains since Covid and the invasion of Ukraine, and its supply chain director put the stakes bluntly.
Today’s supply chain challenges are tomorrow’s hunger crisis.
There is also a political dimension that markets cannot price. When food gets scarce, governments do not behave like economists. They behave like politicians. Export bans, hoarding mandates, and panic buying at the national level turned the modest rice shortfall of 2008 into a global crisis, and analysts are already warning that import-dependent nations are the first dominoes.
The 2015-16 Super El Niño, a far weaker event than what is now forecast, threw tens of millions into food stress across Africa and Asia. This one is projected to be stronger, and it arrives with fertilizer already rationed by price and shipping lanes already contested by missiles.
What Joseph Knew
Scripture does not treat preparation for lean years as faithlessness. It treats it as wisdom delivered in advance to those willing to act on it.
Behold, there come seven years of great plenty throughout all the land of Egypt: And there shall arise after them seven years of famine; and all the plenty shall be forgotten in the land of Egypt.
Joseph did not respond to that warning with a hashtag or a committee. He stored grain during the years of abundance, and when the famine came, Egypt stood while its neighbors begged. The lesson is not that famine is certain. It is that the time to prepare is precisely when preparation still looks optional.
Nobody who filled a pantry in a year of plenty has ever regretted it, and nobody standing in an empty aisle has ever been glad he waited for certainty.
None of this calls for panic, and panic is the enemy of sound judgment anyway. It calls for the same unglamorous prudence our grandparents considered ordinary. Keep some cash margin, know your local growers, and put real food in deep storage while it is cheap and available, because the entire arc of this story is that cheap and available is a closing window.
Families looking for a straightforward place to start can visit Heaven’s Harvest and use promo code Patriot for 15 percent off long-term storable food. The forecasts may yet soften, the strait may yet reopen, and we should pray they do. But hope is a fine thing to hold and a foolish thing to eat.
