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(The Epoch Times)—New research suggests that modern processed food consumption may be fueling colorectal cancer growth, revealing a link between dietary choices and the inflammatory processes that could drive tumor development.
The study, published in Gut on Tuesday, found that chronic inflammation in colorectal cancer (CRC) stems from an abundance of pro-inflammatory omega-6 fats in tumors and insufficient omega-3 fats to neutralize the inflammation. This imbalance hinders the body’s ability to heal and promotes cancer growth.
Both the pro-inflammatory omega-6 and anti-inflammatory omega-3 fats must be obtained through diet, with omega-6 fats being highly prevalent in ultra-processed foods.
“Our presumption—an association, not a cause at this point in time—is that omega-6-rich diets create more pro-inflammatory building blocks, which enzymes in tumors and the body turn into pro-inflammatory fats,” Dr. Timothy Yeatman, professor of surgery at the University of South Florida (USF) Health Morsani College of Medicine, associate center director for Translational Research and Innovation at the Tampa General Hospital (TGH) Cancer Institute, and a corresponding author of the study, told The Epoch Times.
Diet Shapes Cancer Risk
For the study, scientists from the USF and TGH Cancer Institute examined the role of fats and the genes involved in fat metabolism in CRC. They studied 81 pairs of CRC tumor tissue and healthy tissue, focusing on how the body creates and breaks down fats, which can influence inflammation and cancer growth.
The researchers found that high levels of pro-inflammatory omega-6 fats like linolenic acids (LA) and arachidonic acids (AA) drove the cancer.
The findings indicate that diets high in omega-6 fatty acids may contribute to inflammation that facilitates cancer growth.
The Role of Omega-6 Fatty Acids
Excessive intake of omega-6 fatty acids like LAs found in ultra-processed foods and seed oils results in an overproduction of AA in the body. AA is a precursor that gives rise to more pro-inflammatory molecules that can exacerbate inflammation and promote tumor growth.
The body breaks down these omega-6 fatty acids into inflammatory molecules called leukotrienes, Yeatman said, “and that’s what we found in the tumors.”
Leukotrienes activate immune cells, amplify inflammation, and damage tissues, creating an environment conducive to tumor growth in CRC patients.
Ultra-processed foods include meat products such as sausages, hotdogs, chips, sweetened and alcoholic drinks, mass-produced bread, condiments, and ice cream.
Inflammation: A Strong Link to Diet
In healthy tissues, the body transitions from inflammation to healing through a process called lipid class switching, where pro-inflammatory molecules shift to anti-inflammatory fats like prostaglandins, which signal tissue repair.
Inadequate or ineffective levels of prostaglandin leads to defective class switching, resulting in unresolved inflammation. Prostaglandin also prevents the body from turning omega-6 fatty acids into inflammatory leukotrienes.
The research team observed that CRC tumors produce excessive pro-inflammatory molecules while exhibiting 70 percent lower levels of prostaglandins, essential for resolving inflammation. This deficiency disrupts the lipid class-switching process, perpetuating an environment that promotes tumor growth and survival.
Chronic inflammation fosters a microenvironment conducive to immunosuppression, allowing genetic mutations to persist and ultimately manifest as cancer, Yeatman said.
“We found that over the decades, starting around the 50s, the levels of omega-6 in our body fat have increased dramatically,” he added. “So what’s changed in our diet since then? It’s largely the rise of ultra-processed foods and big agriculture, driven by making food production much cheaper. As a result, less expensive seed oils are used as opposed to more pro-resolving oils, like olive and avocado oils.”
Problematic Immune Cells
Specialized white blood cells, which promoted inflammation in the tumors studied, were also key contributors to CRC. These immune cells initially get drawn to the tumor site to kill the cancer but instead become transformed to facilitate tumor growth.
Yeatman said that this behavior has been observed in other cancers.
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“The same processes are likely involved in heart disease, in diabetes, in Alzheimer’s disease,” he added.
What Can Be Done?
Yeatman said we should be mindful of our diets and look at ingredient labels.
“These results (study findings) underscore the need for additional studies that explore what specifically in our diet drives a person’s risk of tumor formation,” Dr. Raaj Mehta, instructor in medicine at Harvard Medical School, attending physician at Massachusetts General Hospital, and not part of the study, told The Epoch Times. “Prevention is essential. We need better ways to counsel our patients about what not to eat and why.
“Hundreds of studies have shown a connection between what we eat and our risk for colorectal cancer. We think this may be mediated by the trillions of bacteria in our digestive tract.”
While little is known about how preservatives and artificial sweeteners affect the microbiome, Yeatman said the microbiome is a critical component in cancer development because it’s the microbiome that processes fats and turns them into different compounds.
“We are supersaturated with arachidonic acid, which is omega-6,” he said. As omega-6 is an essential fatty acid, Yeatman emphasized that he is not saying it’s a bad oil but that too much of anything is bad. “So you should be eating a balanced one-to-one ratio.”
The findings of this study also introduce the concept of resolution medicine, a natural approach to treating inflammation. “It’s based on a concept that natural agents may induce lipid class switching,” Yeatman said.
The study opens the door for new avenues for treatment alongside traditional methods, including resolvin therapies, which use natural agents such as frankincense, cannabidiol (CBD) oil, and celastrol to support this metabolic shift, gene targeting to alter pro-inflammatory pathways, and reprogramming the tumor microenvironment to enhance anti-inflammatory responses.
Five Things New “Preppers” Forget When Getting Ready for Bad Times Ahead
The preparedness community is growing faster than it has in decades. Even during peak times such as Y2K, the economic downturn of 2008, and Covid, the vast majority of Americans made sure they had plenty of toilet paper but didn’t really stockpile anything else.
Things have changed. There’s a growing anxiety in this presidential election year that has prompted more Americans to get prepared for crazy events in the future. Some of it is being driven by fearmongers, but there are valid concerns with the economy, food supply, pharmaceuticals, the energy grid, and mass rioting that have pushed average Americans into “prepper” mode.
There are degrees of preparedness. One does not have to be a full-blown “doomsday prepper” living off-grid in a secure Montana bunker in order to be ahead of the curve. In many ways, preparedness isn’t about being able to perfectly handle every conceivable situation. It’s about being less dependent on government for as long as possible. Those who have proper “preps” will not be waiting for FEMA to distribute emergency supplies to the desperate masses.
Below are five things people new to preparedness (and sometimes even those with experience) often forget as they get ready. All five are common sense notions that do not rely on doomsday in order to be useful. It may be nice to own a tank during the apocalypse but there’s not much you can do with it until things get really crazy. The recommendations below can have places in the lives of average Americans whether doomsday comes or not.
Note: The information provided by this publication or any related communications is for informational purposes only and should not be considered as financial advice. We do not provide personalized investment, financial, or legal advice.
Secured Wealth
Whether in the bank or held in a retirement account, most Americans feel that their life’s savings is relatively secure. At least they did until the last couple of years when de-banking, geopolitical turmoil, and the threat of Central Bank Digital Currencies reared their ugly heads.
It behooves Americans to diversify their holdings. If there’s a triggering event or series of events that cripple the financial systems or devalue the U.S. Dollar, wealth can evaporate quickly. To hedge against potential turmoil, many Americans are looking in two directions: Crypto and physical precious metals.
There are huge advantages to cryptocurrencies, but there are also inherent risks because “virtual” money can become challenging to spend. Add in the push by central banks and governments to regulate or even replace cryptocurrencies with their own versions they control and the risks amplify. There’s nothing wrong with cryptocurrencies today but things can change rapidly.
As for physical precious metals, many Americans pay cash to keep plenty on hand in their safe. Rolling over or transferring retirement accounts into self-directed IRAs is also a popular option, but there are caveats. It can often take weeks or even months to get the gold and silver shipped if the owner chooses to close their account. This is why Genesis Gold Group stands out. Their relationship with the depositories allows for rapid closure and shipping, often in less than 10 days from the time the account holder makes their move. This can come in handy if things appear to be heading south.
Lots of Potable Water
One of the biggest shocks that hit new preppers is understanding how much potable water they need in order to survive. Experts claim one gallon of water per person per day is necessary. Even the most conservative estimates put it at over half-a-gallon. That means that for a family of four, they’ll need around 120 gallons of water to survive for a month if the taps turn off and the stores empty out.
Being near a fresh water source, whether it’s a river, lake, or well, is a best practice among experienced preppers. It’s necessary to have a water filter as well, even if the taps are still working. Many refuse to drink tap water even when there is no emergency. Berkey was our previous favorite but they’re under attack from regulators so the Alexapure systems are solid replacements.
For those in the city or away from fresh water sources, storage is the best option. This can be challenging because proper water storage containers take up a lot of room and are difficult to move if the need arises. For “bug in” situations, having a larger container that stores hundreds or even thousands of gallons is better than stacking 1-5 gallon containers. Unfortunately, they won’t be easily transportable and they can cost a lot to install.
Water is critical. If chaos erupts and water infrastructure is compromised, having a large backup supply can be lifesaving.
Pharmaceuticals and Medical Supplies
There are multiple threats specific to the medical supply chain. With Chinese and Indian imports accounting for over 90% of pharmaceutical ingredients in the United States, deteriorating relations could make it impossible to get the medicines and antibiotics many of us need.
Stocking up many prescription medications can be hard. Doctors generally do not like to prescribe large batches of drugs even if they are shelf-stable for extended periods of time. It is a best practice to ask your doctor if they can prescribe a larger amount. Today, some are sympathetic to concerns about pharmacies running out or becoming inaccessible. Tell them your concerns. It’s worth a shot. The worst they can do is say no.
If your doctor is unwilling to help you stock up on medicines, then Jase Medical is a good alternative. Through telehealth, they can prescribe daily meds or antibiotics that are shipped to your door. As proponents of medical freedom, they empathize with those who want to have enough medical supplies on hand in case things go wrong.
Energy Sources
The vast majority of Americans are locked into the grid. This has proven to be a massive liability when the grid goes down. Unfortunately, there are no inexpensive remedies.
Those living off-grid had to either spend a lot of money or effort (or both) to get their alternative energy sources like solar set up. For those who do not want to go so far, it’s still a best practice to have backup power sources. Diesel generators and portable solar panels are the two most popular, and while they’re not inexpensive they are not out of reach of most Americans who are concerned about being without power for extended periods of time.
Natural gas is another necessity for many, but that’s far more challenging to replace. Having alternatives for heating and cooking that can be powered if gas and electric grids go down is important. Have a backup for items that require power such as manual can openers. If you’re stuck eating canned foods for a while and all you have is an electric opener, you’ll have problems.
Don’t Forget the Protein
When most think about “prepping,” they think about their food supply. More Americans are turning to gardening and homesteading as ways to produce their own food. Others are working with local farmers and ranchers to purchase directly from the sources. This is a good idea whether doomsday comes or not, but it’s particularly important if the food supply chain is broken.
Most grocery stores have about one to two weeks worth of food, as do most American households. Grocers rely heavily on truckers to receive their ongoing shipments. In a crisis, the current process can fail. It behooves Americans for multiple reasons to localize their food purchases as much as possible.
Long-term storage is another popular option. Canned foods, MREs, and freeze dried meals are selling out quickly even as prices rise. But one component that is conspicuously absent in shelf-stable food is high-quality protein. Most survival food companies offer low quality “protein buckets” or cans of meat, but they are often barely edible.
Prepper All-Naturals offers premium cuts of steak that have been cooked sous vide and freeze dried to give them a 25-year shelf life. They offer Ribeye, NY Strip, and Tenderloin among others.
Having buckets of beans and rice is a good start, but keeping a solid supply of high-quality protein isn’t just healthier. It can help a family maintain normalcy through crises.
Prepare Without Fear
With all the challenges we face as Americans today, it can be emotionally draining. Citizens are scared and there’s nothing irrational about their concerns. Being prepared and making lifestyle changes to secure necessities can go a long way toward overcoming the fears that plague us. We should hope and pray for the best but prepare for the worst. And if the worst does come, then knowing we did what we could to be ready for it will help us face those challenges with confidence.
